diff --git a/coccinelle/run-coccinelle.sh b/coccinelle/run-coccinelle.sh
index 4d882112e6..be80a76a5f 100755
--- a/coccinelle/run-coccinelle.sh
+++ b/coccinelle/run-coccinelle.sh
@@ -1,10 +1,25 @@
 #!/bin/bash -e
 
+# Exclude following paths from the Coccinelle transformations
+EXCLUDED_PATHS=(
+    "src/boot/efi/*"
+    "src/shared/linux/*"
+    "src/basic/linux/*"
+    # Symlinked to test-bus-vtable-cc.cc, which causes issues with the IN_SET macro
+    "src/libsystemd/sd-bus/test-bus-vtable.c"
+)
+
 top="$(git rev-parse --show-toplevel)"
-files="$(git ls-files ':/*.[ch]')"
 iso_defs="$top/coccinelle/systemd-definitions.iso"
 args=
 
+# Create an array from files tracked by git...
+mapfile -t files < <(git ls-files ':/*.[ch]')
+# ...and filter everything that matches patterns from EXCLUDED_PATHS
+for excl in "${EXCLUDED_PATHS[@]}"; do
+    files=(${files[@]//$excl})
+done
+
 case "$1" in
     -i)
         args="$args --in-place"
@@ -22,7 +37,7 @@ for SCRIPT in ${@-$top/coccinelle/*.cocci} ; do
     TMPFILE=`mktemp`
     echo "+ spatch --sp-file $SCRIPT $args ..."
     parallel --halt now,fail=1 --keep-order --noswap --max-args=20 \
-             spatch --iso-file $iso_defs --sp-file $SCRIPT $args ::: $files \
+             spatch --iso-file $iso_defs --sp-file $SCRIPT $args ::: "${files[@]}" \
              2>"$TMPFILE" || cat "$TMPFILE"
     echo -e "--x-- Processed $SCRIPT --x--\n"
 done